Isaacson rhymes with:
bendickson, derickson, derrickson, dirickson, erichsen, ericksen, erickson, ericson, ericsson, eriksen, erikson, eriksson, errickson, fredericksen, frederickson, frederiksen, fredricksen, fredrickson, fredrikson, friedrichsen, gullickson, gullikson, hellickson, hendricksen, hendrickson, hendriksen, hendrixson, henrichsen, henricksen, henrickson, henriksen, henrikson, hinrichsen
Isaacson sounds like:
iacona, iacono, iason, icahn, ice-nine, iceman, icon, igene, igman, ignominy, igon, iguana, ikon, isackson, isaksen, isakson, ischemia, iseman, isham, ishikawajima, ishman, ism, isom, ison, isoxicam, issam, ixion, izumi